Born in Edinburgh, Hancock studied sociology at Durham University before working as a journalist, writing for a number of British newspapers and magazines. His first three books dealt with international development, including Lords of Poverty (1989), a well-received critique of corruption in the aid system. Beginning with The Sign and the Seal in 1992, he shifted focus to speculative accounts of human prehistory and ancient civilisations, on which he has written a dozen books, most notably Fingerprints of the Gods, The Message of the Sphinx, and Magicians of the Gods. His ideas have been the subject of several films, including the Netflix series Ancient Apocalypse (2022), and Hancock makes regular appearances on the podcast The Joe Rogan Experience to discuss them. He has also written two fantasy novels and in 2013 delivered a controversial TEDx talk promoting the use of ayahuasca.