Monotherapy
- Starting dose: 200 mg BID.
- First dose reduction: 150 mg BID.
- Second dose reduction: 100 mg BID.
- Third dose reduction: 50 mg BID.
- Discontinue if unable to tolerate 50 mg BID.
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Verzenio can be taken every day in both the adjuvant and metastatic setting. 1 150-mg tablet twice daily: in combination with ET 200-mg tablet twice daily: ...
Jan 3, 2024 · When used as monotherapy, the recommended dose of VERZENIO is 200 mg taken orally twice daily. For early breast cancer, continue VERZENIO until ...
Jun 26, 2023 · Ketoconazole is predicted to increase the AUC of abemaciclib by up to 16-fold. In patients with recommended starting doses of 200 mg twice daily ...
Jan 31, 2024 · Dosing · Adults—At first, 150 milligrams (mg) 2 times a day for up to 2 years. Your doctor may adjust your dose as needed or tolerated. · Children ...
Mar 30, 2023 · Dose Adjustments · The recommended starting dose is 200 mg orally twice a day. · The recommended first dose reduction is 150 mg orally twice a day ...
2.1 Recommended Dose and Schedule ... Severe (Grade 3 and 4) neutropenia was observed in patients receiving abemaciclib [see Dosage and Administration (2.2)].
Administer abemaciclib: administer orally TWICE a day (preferably at the same time each day, 12 hours apart); to be swallowed whole with a glass of water; do ...
Instruct patients to take their doses of VERZENIO at approximately the same times every day. If the patient vomits or misses a dose of VERZENIO, instruct the ...
Verzenio (abemaciclib) is a prescription drug that's taken to treat breast cancer. It comes as a tablet you swallow and is usually taken twice per day.